Closed on Aug 27, 2026
Division of Integrative Organismal Systems Core Programs (IOS)
U.S. National Science Foundation · Opportunity number 24-546
Details summarized from the official notice as of Aug 28, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.
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This opportunity is closed as of Aug 27, 2026.
It is kept here for reference. See the related open opportunities below, or check the official listing in case the agency posts a new cycle.
Key facts
| Opportunity number | 24-546 |
|---|---|
| Agency | U.S. National Science Foundation |
| Assistance listing (ALN, formerly CFDA) | 47.074 |
| Posted | Feb 17, 2024 |
| Deadline | Aug 27, 2026 |
| Estimated total program funding | $70,000,000 |
| Cost sharing or matching required | No |
| Funding type | Grant |
| Category | Science technology and other research and development |
| Last updated here | Aug 28, 2026 |
Summary from the notice
The Division of Integrative Organismal Systems (IOS) Core Programs Track supports research to understand why organisms are structured the way they are and function as they do. Proposals are welcomed in all of the core scientific program areas supported by the Division of Integrative Organismal Systems (IOS). Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, development, structure, modification, function, and evolution of the nervous system, biomechanics and functional morphology, physiological processes, symbioses and microbial interactions, interactions of organisms with biotic and abiotic environments,plant and animal genomics, and animal behavior. Proposals should focus on organisms as a fundamental unit of biological organization. Principal Investigators are encouraged to apply systems approaches that will lead to conceptual and theoretical insights and predictions about emergent organismal properties.
The IntBIOTrackinvites submission of collaborative proposals totackle bold questions in biology thatrequire an integrated approach to make substantive progress. Integrative biological research spans subdisciplines and incorporates cutting-edge methods, tools, and concepts from each to produce groundbreaking biological discovery that is synergistic, such that the whole is greater than the sum of the parts. The research should produce a novel, holistic understanding of how biological systems function and interact across different scales of organization, e.g., from molecules to cells, tissues to organisms, species to ecosystems and the entire Earth.Where appropriate, projects should apply experimental strategies, modeling, integrative analysis, advanced computation, or other research approaches to stimulate new discovery and general theory in biology.
Who can apply
The official notice lists these applicant types as eligible:
- Others named in the notice (see the eligibility text)
Not listed as eligible
- Small businesses
- Nonprofits
- Colleges and universities
- State governments
- Local governments
- Tribal governments and organizations
- Larger for-profit companies
- Individuals
Unless the eligibility text in the notice names you, this opportunity is probably not for you.
Eligibility details from the notice
*Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.
Registrations you will likely need
Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.
- SAM.gov registration for your organization, which also gives you a Unique Entity ID (UEI). Registration is free.
- A Login.gov account, which Grants.gov uses for sign-in.
- A Grants.gov applicant registration linked to your organization's UEI.
Past awards for this program
Totals for assistance listing 47.074 from public USASpending.gov data, as of Sep 23, 2026. Past awards do not predict future funding.
| Year | Listing | Awards | Total | Average |
|---|---|---|---|---|
| 2026 | 47.074 | 7 | $187,602,317 | $26,800,331 |
| 2025 | 47.074 | 6 | $175,835,355 | $29,305,893 |
| 2024 | 47.074 | 6 | $201,363,355 | $33,560,559 |
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