Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation
U.S. National Science Foundation · Opportunity number 24-561
Details summarized from the official notice as of May 5, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.
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Key facts
| Opportunity number | 24-561 |
|---|---|
| Agency | U.S. National Science Foundation Department of Health and Human Services |
| Assistance listing (ALN, formerly CFDA) | 47.049, 47.070, 93.310 |
| Posted | Mar 23, 2024 |
| Deadline | May 4, 2026 |
| Award ceiling | $800,000 |
| Expected number of awards | 46 |
| Estimated total program funding | $14,000,000 |
| Cost sharing or matching required | Yes |
| Funding type | Grant |
| Category | Health |
| Last updated here | May 5, 2026 |
Summary from the notice
Who can apply
The official notice lists these applicant types as eligible:
- Others named in the notice (see the eligibility text)
Not listed as eligible
- Small businesses
- Nonprofits
- Colleges and universities
- State governments
- Local governments
- Tribal governments and organizations
- Larger for-profit companies
- Individuals
Unless the eligibility text in the notice names you, this opportunity is probably not for you.
Eligibility details from the notice
Eligibility for this program is statutorily limited to public entities such as: State governments; Indian or tribal organizations (as defined in Section 4[b] and Section 4[c] of the Indian Self-Determination and Education Assistance Act); Governmental units within political subdivisions of a State, such as a county, city or town; District of Columbia government; and Commonwealth of Puerto Rico, Northern Mariana Islands, Virgin Islands, Guam, American Samoa and Trust Territory of the Pacific Islands (now Palau, Micronesia and the Marshall Islands). The purpose of this RFA is to expand and sustain systems of care, priority will be given to applications that demonstrate the ability to engage in planning activities that reflect the greatest geographic area and that represent the likelihood for extensive and wide-ranging policy and program transformation (i.e., Statewide, territory-wide, and tribal). A maximum of one award will be made per State, Territory, Indian or Tribal Organization, or the District of Columbia. The applicant, whether a state, or a political entity other than a state, must provide evidence of commitment for SOC expansion by including a letter of support from the Governor (or designee), or the commensurate- level tribal, or territorial representative or (designee). The letter must identify how the applicant will expand efforts to a broader level, and an explanation of how sustainability will be accomplished. The letter should also provide evidence of...
Cost sharing: this notice requires cost sharing or matching funds. Check the notice for the required share and what counts toward it.
Registrations you will likely need
Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.
- SAM.gov registration for your organization, which also gives you a Unique Entity ID (UEI). Registration is free.
- A Login.gov account, which Grants.gov uses for sign-in.
- A Grants.gov applicant registration linked to your organization's UEI.
Past awards for this program
Totals for assistance listing 47.049, 47.070, 93.310 from public USASpending.gov data, as of Sep 23, 2026. Past awards do not predict future funding.
| Year | Listing | Awards | Total | Average |
|---|---|---|---|---|
| 2026 | 47.070 | 7 | $143,594,466 | $20,513,495 |
| 2026 | 47.049 | 16 | $1,790,278,386 | $111,892,399 |
| 2025 | 47.070 | 7 | $158,110,465 | $22,587,209 |
| 2025 | 47.049 | 21 | $1,947,852,199 | $92,754,867 |
| 2024 | 47.070 | 5 | $115,904,772 | $23,180,954 |
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