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Closed on May 4, 2026

Foundations for Digital Twins as Catalyzers of Biomedical Technological Innovation

U.S. National Science Foundation · Opportunity number 24-561

Details summarized from the official notice as of May 5, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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This opportunity is closed as of May 4, 2026. It is kept here for reference. See the related open opportunities below, or check the official listing in case the agency posts a new cycle.

Key facts

Opportunity number24-561
AgencyU.S. National Science Foundation
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)47.049, 47.070, 93.310
PostedMar 23, 2024
DeadlineMay 4, 2026
Award ceiling$800,000
Expected number of awards46
Estimated total program funding$14,000,000
Cost sharing or matching requiredYes
Funding typeGrant
CategoryHealth
Last updated hereMay 5, 2026

Summary from the notice

The Substance Abuse and Mental Health Services Administration's, Center for Mental Health Services is accepting applications for fiscal year (FY) 2011 for Planning Grants for Expansion of the Comprehensive Community Mental Health Services for Children and their Families (System of Care Expansion Planning Grants). The purpose of these grants is to develop a comprehensive strategic plan for improving and expanding services provided by systems of care (SOC) for children and youth with serious emotional disturbances and their families.A "system of care" is an organizational philosophy and framework that involves collaboration across government and private agencies, providers, families, and youth for the purpose of improving access and expanding the array of coordinated community-based, culturally and linguistically competent services and supports for children and youth with a serious emotional disturbance and their families. Since the inception of the Comprehensive Community Mental Health Services for Children and Their Families Program (i.e., Children's Mental Health Initiative or CMHI) in 1992 by an act of Congress, the SOC approach has served as the conceptual and philosophical framework for systemic reform in children's mental health.An estimated 4.5 to 6.3 million children and youth in the United States suffer from a serious mental health condition (about 10%) and 20% have a diagnosable mental disorder. Approximately 65% to 80% of these children and youth do not receive the specialty mental health services and supports they need. In addition, the onset for 50% of adult mental health disorders is by age 14, and for 75% of adults it is age 24, and yet resources are limited for children, youth and their families. Suicide is the third leading cause of death in individuals in the 15-24 year age group and approximately one in five adolescents and young adults experience suicidal ideation every year.Accumulating research and evaluation results from the CMHI over the last 15 years have demonstrated that, when a SOC approach is implemented and sustained, children, youth and families experience both short and long-term benefits, including: improvement in clinical and functional outcomes, significant reductions in suicide attempts by youth, improvement in school attendance and performance, reduction in contacts with law enforcement, and reduction of reliance on inpatient settings for care. Data show that caregivers of children served within systems of care experienced reduced strain associated with caring for a child who has a serious mental health condition, more adequate resources, fewer missed days of work, and improvement in overall family functioning. Research has demonstrated that systems of care have a positive effect on the structure, organization, and availability of services for children and youth with serious mental health needs and their families. The intent of the System of Care Expansion Planning Grants is to build and expand upon the progress achieved in the CMHI program during the last 18 years in addressing the mental health needs of children, youth and families. SAMHSA expects that these grants will help facilitate State/Tribal wide adoption of the System of Care framework and increase State Medicaid and other third party reimbursement for the System of Care spectrum of services and supports. Applicants are expected to create comprehensive and sustainable plans for infrastructure, services, and supports that are consistent with the requirements authorized under Section 561 of the Public Health Service Act, as amended. This announcement addresses Healthy People Mental Health and Mental Disorders Topic Area HP 2020.The SOC Expansion Planning Grants closely align with SAMHSA's Trauma and Justice and Health Reform Strategic Initiatives by focusing resources on reducing the impact of substance abuse and mental illness on American communities and addressing the behavioral health impacts of trauma through a systematic public health approach.

Who can apply

The official notice lists these applicant types as eligible:

  • Others named in the notice (see the eligibility text)

Not listed as eligible

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies
  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Eligibility for this program is statutorily limited to public entities such as: State governments; Indian or tribal organizations (as defined in Section 4[b] and Section 4[c] of the Indian Self-Determination and Education Assistance Act); Governmental units within political subdivisions of a State, such as a county, city or town; District of Columbia government; and Commonwealth of Puerto Rico, Northern Mariana Islands, Virgin Islands, Guam, American Samoa and Trust Territory of the Pacific Islands (now Palau, Micronesia and the Marshall Islands). The purpose of this RFA is to expand and sustain systems of care, priority will be given to applications that demonstrate the ability to engage in planning activities that reflect the greatest geographic area and that represent the likelihood for extensive and wide-ranging policy and program transformation (i.e., Statewide, territory-wide, and tribal). A maximum of one award will be made per State, Territory, Indian or Tribal Organization, or the District of Columbia. The applicant, whether a state, or a political entity other than a state, must provide evidence of commitment for SOC expansion by including a letter of support from the Governor (or designee), or the commensurate- level tribal, or territorial representative or (designee). The letter must identify how the applicant will expand efforts to a broader level, and an explanation of how sustainability will be accomplished. The letter should also provide evidence of...

Cost sharing: this notice requires cost sharing or matching funds. Check the notice for the required share and what counts toward it.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

Past awards for this program

Totals for assistance listing 47.049, 47.070, 93.310 from public USASpending.gov data, as of Sep 23, 2026. Past awards do not predict future funding.

YearListingAwardsTotalAverage
2026 47.070 7 $143,594,466 $20,513,495
2026 47.049 16 $1,790,278,386 $111,892,399
2025 47.070 7 $158,110,465 $22,587,209
2025 47.049 21 $1,947,852,199 $92,754,867
2024 47.070 5 $115,904,772 $23,180,954

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