Open federal grants for nonprofits
472 open opportunities as of Oct 16, 2026.
Independent platform. Not affiliated with or endorsed by any government agency. Data from public federal sources.
Many federal programs list nonprofits as eligible, and notices often split them into two groups: nonprofits with 501(c)(3) status from the IRS and nonprofits without it. Check which group the notice names. Colleges and universities are usually listed separately even when they are nonprofits.
The list below shows every open opportunity in our database whose official notice lists nonprofits as an eligible applicant type. Each listing links to a summary page and to the official notice.
Being in an eligible group is only the first check. Read the eligibility section of each notice for location, program focus, cost sharing and other conditions before you start an application.
Open opportunities
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)
National Institutes of Health · PAR-25-070
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
National Institutes of Health · PAR-25-032
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)
National Institutes of Health · PAR-25-079
Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)
National Institutes of Health · PAR-25-235
Oceanographic Facilities and Equipment Support
U.S. National Science Foundation · 23-525
Title X Family Planning Services Grants
Office of the Assistant Secretary for Health · PA-FPH-27-001
Discovery of the Genetic Basis of Childhood Cancers and of Congenital Anomalies: Gabriella Miller Kids First Pediatric Research Program (X01 Clinical Trial Not Allowed)
National Institutes of Health · PAR-27-071
Glioblastoma Therapeutics Network (GTN) (U19 Clinical Trial Required)
National Institutes of Health · RFA-CA-27-005
Fiscal Year (FY) 2027 AmeriCorps State and National Competitive Grants
AmeriCorps · AC-08-28-26
National Digital Newspaper Program
National Endowment for the Humanities · 20270113-PJ
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
National Institutes of Health · RFA-NS-25-023
National Bycatch Reduction Engineering Program (BREP) - FY2026/27
DOC NOAA - ERA Production · NOAA-NMFS-FHQ-2027-33398
Medical Scientist Training Program (MSTP) (T32)
National Institutes of Health · PAR-24-128
ROSS Rapid Response Program
Department of Housing and Urban Development · PIH-ROSS-26-001
Cancer Advancement through Partnerships in Research and Infrastructure (CAPRI) (U54 Clinical Trial Optional)
National Institutes of Health · PAR-28-062
National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)
National Institutes of Health · PAR-26-138
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)
National Institutes of Health · RFA-DA-28-012
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
National Institutes of Health · RFA-DA-28-011
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)
National Institutes of Health · PAR-24-268
Diabetes Research Centers (P30 Clinical Trial Optional)
National Institutes of Health · RFA-DK-26-310
Frequently asked questions
Does being listed as eligible mean my organization qualifies?
No. The applicant type is only the first filter. Most notices add more conditions, such as location, program focus, matching funds or prior experience. Read the eligibility section of the official notice before you apply.
Is GovGrantsUSA a government website?
No. GovGrantsUSA is an independent platform operated by VRLY Ventures LLC. It is not affiliated with or endorsed by any government agency. Opportunity details are summarized from public federal sources such as Grants.gov.
Does it cost anything to apply for a federal grant?
Searching for and applying to federal grants on Grants.gov is free. Be wary of anyone who asks for a fee to "release" a grant or guarantees an award.
How current is this information?
Listings are refreshed from public federal data every day, and each page shows when it was last updated. Agencies can change or cancel a notice at any time, so always confirm details in the official notice.
What do I need before I can apply?
Most applicants through Grants.gov need an active SAM.gov registration with a Unique Entity ID (UEI), a Login.gov account and a Grants.gov account linked to their organization. Registration can take several weeks, so start early.