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Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)

National Institutes of Health · Opportunity number PAR-24-329

View the official notice on Grants.gov
151 days left (deadline Mar 16, 2027)

Details summarized from the official notice as of Oct 15, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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Key facts

Opportunity numberPAR-24-329
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.279
PostedJan 8, 2025
DeadlineMar 16, 2027
Cost sharing or matching requiredNo
Funding typeGrant
CategoryEducation
Last updated hereOct 15, 2026

Summary from the notice

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research for people who use drugs. For the purposes of this NOFO, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons living with HIV.

Who can apply

The official notice lists these applicant types as eligible:

  • Nonprofits without 501(c)(3) status (other than colleges)
  • Special district governments
  • Nonprofits with 501(c)(3) status (other than colleges)
  • Other Native American tribal organizations
  • Private colleges and universities
  • Public and Indian housing authorities
  • Others named in the notice (see the eligibility text)
  • City or township governments
  • County governments
  • Small businesses
  • State governments
  • Independent school districts
  • Federally recognized tribal governments
  • For-profit organizations other than small businesses
  • Public and state colleges and universities

Who should take a closer look

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies

Not listed as eligible

  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

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