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Closed on May 7, 2026

Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional)

National Institutes of Health · Opportunity number PAR-25-036

Details summarized from the official notice as of May 8, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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This opportunity is closed as of May 7, 2026. It is kept here for reference. See the related open opportunities below, or check the official listing in case the agency posts a new cycle.

Key facts

Opportunity numberPAR-25-036
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.866, 93.242
PostedNov 6, 2024
DeadlineMay 7, 2026
Cost sharing or matching requiredNo
Funding typeGrant
CategoryHealth
Last updated hereMay 8, 2026

Summary from the notice

This Notice of Funding Opportunity (NOFO) invites research grant applications that propose the development and evaluation of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in human brain and the incorporation of, pilot or clinical feasibility evaluation from previously collected data in pre-clinical studies. These studies are expected to provide the requisite data needed to advance promising PET ligands for use in clinical research.

Who can apply

The official notice lists these applicant types as eligible:

  • County governments
  • Nonprofits with 501(c)(3) status (other than colleges)
  • Independent school districts
  • Small businesses
  • Private colleges and universities
  • Public and state colleges and universities
  • City or township governments
  • Special district governments
  • State governments
  • Public and Indian housing authorities
  • Nonprofits without 501(c)(3) status (other than colleges)
  • Other Native American tribal organizations
  • Federally recognized tribal governments
  • Others named in the notice (see the eligibility text)
  • For-profit organizations other than small businesses

Who should take a closer look

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies

Not listed as eligible

  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

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