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Cancer Prevention and Control Clinical Trials Planning Grant Program (U34 Clinical Trials Optional)

National Institutes of Health · Opportunity number PAR-25-103

View the official notice on Grants.gov
374 days left (deadline Oct 25, 2027)

Details summarized from the official notice as of Oct 15, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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Key facts

Opportunity numberPAR-25-103
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.399
PostedNov 5, 2024
DeadlineOct 25, 2027
Cost sharing or matching requiredNo
Funding typeCooperative agreement
CategoryEducation
Last updated hereOct 15, 2026

Summary from the notice

The purpose of this NOFO is to facilitate well planned clinical trials across the cancer prevention and control spectrum aimed at improving prevention/ interception, cancer-related health behaviors, screening, early detection, healthcare delivery, management of treatment-related symptoms, supportive care, and the long-term outcomes of cancer survivors. Although the scientific literature or preliminary data may provide the rationale for conducting a clinical trial, investigators often lack critical information about the study population, accrual challenges, intervention, outcome/ endpoints, data/statistical challenges or operational risks necessary to finalize the trial protocol completely. These information gaps can result in multiple protocol changes before and after trial start-up, leading to the need for additional time and expenses that may prevent study completion. Further, the suitability and feasibility of new trial designs, which minimize infrastructure and reduce costs may need to be tested in the context of a particular intervention, at-risk group, symptom or venue. Preparatory studies may fill information gaps and address unknowns, improving trial design and knowledge of trial feasibility and thus saving NCI time and money.

Who can apply

The official notice lists these applicant types as eligible:

  • Small businesses
  • Independent school districts
  • State governments
  • For-profit organizations other than small businesses
  • City or township governments
  • Federally recognized tribal governments
  • Nonprofits without 501(c)(3) status (other than colleges)
  • Nonprofits with 501(c)(3) status (other than colleges)
  • Private colleges and universities
  • Special district governments
  • Public and Indian housing authorities
  • Others named in the notice (see the eligibility text)
  • County governments
  • Public and state colleges and universities
  • Other Native American tribal organizations

Who should take a closer look

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies

Not listed as eligible

  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

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