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Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial Not Allowed)

National Institutes of Health · Opportunity number RFA-AI-28-031

View the official notice on Grants.gov
224 days left (deadline May 28, 2027)

Details summarized from the official notice as of Oct 15, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

Independent platform. Not affiliated with or endorsed by any government agency. Data from public federal sources.

Key facts

Opportunity numberRFA-AI-28-031
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.310, 93.855
PostedOct 2, 2026
DeadlineMay 28, 2027
Award ceiling$3,500,000
Estimated total program funding$33,000,000
Cost sharing or matching requiredNo
Funding typeCooperative agreement
CategoryHealth
Last updated hereOct 15, 2026

Summary from the notice

The purpose of this notice of funding opportunity (NOFO) is to support multidisciplinary consortia of structural biologists, microbiologists, and associated experts to solve complex biological structures related to the prevention, treatment, and cure of HIV and other infectious diseases. Centers are expected to facilitate new collaborations, leverage shared resources, offer services and resources to the research community, and train the next generation of scientists engaged in structural biology of infectious diseases.

Who can apply

The official notice lists these applicant types as eligible:

  • Federally recognized tribal governments
  • City or township governments
  • Public and state colleges and universities
  • Public and Indian housing authorities
  • State governments
  • Others named in the notice (see the eligibility text)
  • Private colleges and universities
  • Other Native American tribal organizations
  • Special district governments
  • Nonprofits without 501(c)(3) status (other than colleges)
  • County governments
  • For-profit organizations other than small businesses
  • Small businesses
  • Nonprofits with 501(c)(3) status (other than colleges)
  • Independent school districts

Who should take a closer look

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies

Not listed as eligible

  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

Past awards for this program

Totals for assistance listing 93.310, 93.855 from public USASpending.gov data, as of Mar 26, 2026. Past awards do not predict future funding.

YearListingAwardsTotalAverage
2026 93.855 1 $1,062,954,652 $1,062,954,652

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