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Closed on Aug 17, 2026

NIH Director’s New Innovator Award (DP2 Clinical Trial Optional)

National Institutes of Health · Opportunity number RFA-RM-27-002

Details summarized from the official notice as of Jun 28, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.

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This opportunity is closed as of Aug 17, 2026. It is kept here for reference. See the related open opportunities below, or check the official listing in case the agency posts a new cycle.

Key facts

Opportunity numberRFA-RM-27-002
AgencyNational Institutes of Health
Department of Health and Human Services
Assistance listing (ALN, formerly CFDA)93.310
PostedJun 26, 2026
DeadlineAug 17, 2026
Award ceiling$475,000
Award floor$475,000
Expected number of awards30
Estimated total program funding$23,000,000
Cost sharing or matching requiredNo
Funding typeGrant
CategoryHealth
Last updated hereJun 28, 2026

Summary from the notice

The NIH Director"s New Innovator Award supports early-stage investigators of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. The NIH Director's New Innovator Award complements other ongoing efforts by NIH and its Institutes and Centers to fund early-stage investigators. The NIH Director"s New Innovator Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Who can apply

The official notice lists these applicant types as eligible:

  • Others named in the notice (see the eligibility text)
  • Federally recognized tribal governments
  • County governments
  • Nonprofits without 501(c)(3) status (other than colleges)
  • Private colleges and universities
  • Special district governments
  • State governments
  • For-profit organizations other than small businesses
  • Other Native American tribal organizations
  • Independent school districts
  • Public and state colleges and universities
  • City or township governments
  • Small businesses
  • Public and Indian housing authorities
  • Nonprofits with 501(c)(3) status (other than colleges)

Who should take a closer look

  • Small businesses
  • Nonprofits
  • Colleges and universities
  • State governments
  • Local governments
  • Tribal governments and organizations
  • Larger for-profit companies

Not listed as eligible

  • Individuals

Unless the eligibility text in the notice names you, this opportunity is probably not for you.

Eligibility details from the notice

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Registrations you will likely need

Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.

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