NIH Director’s Early Independence Award (DP5 Clinical Trial Optional)
National Institutes of Health · Opportunity number RFA-RM-27-004
Details summarized from the official notice as of Sep 11, 2026. Always confirm eligibility, deadlines and requirements in the official notice before applying.
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Key facts
| Opportunity number | RFA-RM-27-004 |
|---|---|
| Agency | National Institutes of Health Department of Health and Human Services |
| Assistance listing (ALN, formerly CFDA) | 93.310 |
| Posted | Jun 26, 2026 |
| Deadline | Sep 10, 2026 |
| Award ceiling | $350,000 |
| Award floor | $350,000 |
| Expected number of awards | 10 |
| Estimated total program funding | $5,700,000 |
| Cost sharing or matching required | No |
| Funding type | Grant |
| Category | Health |
| Last updated here | Sep 11, 2026 |
Summary from the notice
Who can apply
The official notice lists these applicant types as eligible:
- Small businesses
- Private colleges and universities
- Public and Indian housing authorities
- Other Native American tribal organizations
- Public and state colleges and universities
- Nonprofits without 501(c)(3) status (other than colleges)
- Special district governments
- Others named in the notice (see the eligibility text)
- County governments
- State governments
- For-profit organizations other than small businesses
- Federally recognized tribal governments
- Nonprofits with 501(c)(3) status (other than colleges)
- Independent school districts
- City or township governments
Who should take a closer look
- Small businesses
- Nonprofits
- Colleges and universities
- State governments
- Local governments
- Tribal governments and organizations
- Larger for-profit companies
Not listed as eligible
- Individuals
Unless the eligibility text in the notice names you, this opportunity is probably not for you.
Eligibility details from the notice
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Registrations you will likely need
Most applications submitted through Grants.gov need the following. Registration can take several weeks, so start early. The notice lists the exact requirements.
- SAM.gov registration for your organization, which also gives you a Unique Entity ID (UEI). Registration is free.
- A Login.gov account, which Grants.gov uses for sign-in.
- A Grants.gov applicant registration linked to your organization's UEI.
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